N.A. Switz, M.V. D'Ambrosio, D.A. Fletcher, "Low-cost mobile phone microscopy with a reversed mobile phone camera lens. PLoS One. 2014 May 22;9(5):e95330. doi: 10.1371/journal.pone.0095330. eCollection 2014. [Abstract]

A. Skandarajah, C.D. Reber, N.A. Switz, D.A. Fletcher, "Quantitative Imaging with a Mobile Phone Microscope" PLoS One. 2014 May 13;9(5):e96906. doi: 10.1371/journal.pone.0096906. eCollection 2014. [Abstract]

C.H. Clausen, M.D. Brooks, T.D. Li, P. Grob, G Kemalyan, E. Nogales, K.K. Niyogi, D.A. Fletcher, "Dynamic mechanical responses of Arabidopsis thylakoid membranes during PSII-specific illumination. Biophys J. 2014 May 6;106(9):1864-70. doi: 10.1016/j.bpj.2014.03.016. [Abstract]

C.W. Coyne, K. Patel, J. Heureaux, J. Stachowiak, D.A. Fletcher, A.P. Liu, "Lipid bilayer vesicle generation using microfluidic jetting" J Vis Exp. 2014 Feb 21;(84):e51510. doi: 10.3791/51510. [Abstract]

F.J. Fourniol, T.D. Li, P. Bieling, R.D. Mullins, D.A. Fletcher, T. Surrey, "Micropattern-guided assembly of overlapping pairs of dynamic microtubules" Methods Enzymol. 2014;540:339-60. doi: 10.1016/B978-0-12-397924-7.00019-4. [Abstract]


M.D. Vahey, D.A. Fletcher, "The biology of boundary conditions: cellular reconstitution in one, two, and three dimensions", Curr Opin Cell Biol. 2014 Feb;26:60-8. doi: 10.1016/ Epub 2013 Nov 12. [Abstract]

V.B. Zeldovich, C.H. Clausen, E. Bradford, D.A. Fletcher, E. Maltepe, J.R. Robbins, A.I. Bakardjiev, "Placental syncytium forms a biophysical barrier against pathogen invasion", PLoS Pathog. 2013 Dec;9(12):e1003821. doi: 10.1371/journal.ppat.1003821. Epub 2013 Dec 12. [Abstract]

R.N. Maamari, J.D. Keenan, D.A. Fletcher, T.P. Margolis, "A mobile phone-based retinal camera for portable wide field imaging", Br J Ophthalmol. 2013 Dec 16. doi: 10.1136/bjophthalmol-2013-303797. [Epub ahead of print] [Abstract]

M.C. Good, M.D. Vahey, A. Skandarajah, D.A. Fletcher, R. Heald, "Cytoplasmic volume modulates spindle size during embryogenesis" , Science. 2013 Nov 15;342(6160):856-60. doi: 10.1126/science.1243147. [Abstract]

B.L. Ricca, G. Venugopalan, D.A. Fletcher, "To pull or be pulled: parsing the multiple modes of mechanotransduction", Curr Opin Cell Biol. 2013 Oct;25(5):558-64. doi: 10.1016/ Epub 2013 Jul 2. [Abstract]

S. Barreto, C.H. Clausen, C.M. Perrault, D.A. Fletcher, D. Lacroix, "A multi-structural single cell model of force-induced interactions of cytoskeletal components", Biomaterials. 2013 Aug;34(26):6119-26. doi: 10.1016/j.biomaterials.2013.04.022. Epub 2013 May 21. [Abstract]

D.G. Brownfield, G. Venugopalan, A. Lo, H. Mori, K. Tanner, D.A. Fletcher, M.J. Bissell, "Patterened Collagen Fibers Orient Branching Mammary Epithelium through Distinct Signaling Modules", Curr Biol. 2013 Apr 22;23(8):703-9. doi: 10.1016/j.cub.2013.03.032. Epub 2013 Apr 4. [Article]

A. Tapley, N. Switz, C. Reber, J.L. Davis, C. Miller, J.B. Matovu, W. Worodria, L. Huang, D.A. Fletcher, A. Cattamanchi, "Mobile Digital Fluorescence Microscopy for Diagnosis of Tuberculosis", J Clin Microbiol. 2013 Jun;51(6):1774-8. doi: 10.1128/JCM.03432-12. Epub 2013 Apr 3. [Article]


A. Diz-Muñoz, D.A. Fletcher, O.D. Weiner, "Use the force: membrane tension as an organizer of cell shape and motility", Trends Cell Biol. 2013 Feb;23(2):47-53. doi: 10.1016/j.tcb.2012.09.006. Epub 2012 Nov 2. Review. [Article]

J. Chang, P. Arbeláez, N. Switz, C. Reber, A. Tapley, J.L. Davis, A. Cattamanchi, D.A. Fletcher, J. Malik, "Automated tuberculosis diagnosis using fluorescence images from a mobile microscope", Med Image Comput Comput Assist Interv. 2012;15(Pt 3):345-52. [Article]

J.C. Stachowiak, E.M. Schmid , C.J. Ryan, H.S. Ann, D.Y. Sasaki, M.B. Sherman, P.L. Geissler, D.A. Fletcher, C.C. Hayden, "Membrane bending by protein-protein crowding", Nat Cell Biol. 2012 Sep;14(9):944-9. doi: 10.1038/ncb2561. Epub 2012 Aug 19. [Article]

V.I. Risca, E.B. Wang, O. Chaudhuri, J.J. Chia, P.L. Geissler, D.A. Fletcher, “Actin filament curvature biases branching direction”, Proceedings of the National Academy of Sciences USA, vol 109 issue 8, 2913-2918, February 2012. Epub January 2012. [Article]

A. Crow, K.D. Webster, E. Hohlfeld, W.P. Ng, P. Geissler, D.A. Fletcher, “Contractile equilibriation of single cells to step changes in extracellular stiffness”, Biophysical Journal, vol 102 issue 3, 443-451, February 2012. [Article]

M. Tsai, A. Kita, J. Leach, R. Rounsevell, J.N. Huang, J. Moake, R.E. Ware, D.A. Fletcher, W.A. Lam, “In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology”, The Journal of Clinical Investigation, vol 122 issue 1, 408-418, January 2012. Epub December 2011. [Article]


A. Kita, Y. Sakuri, D.R. Myers, R. Rounsevell, J.N. Huang, T.J. Seok, K. Yu, M.C. Wu, D.A. Fletcher, W.A. Lam, "Microenvironmental geometry guides platelet adhesion and spreading: A quantitative analysis at the single cell level", PLoS ONE, vol 6 issue 10, e26437, October 2011. Epub ahead of print. [Article]

D.L. Richmond, E.M. Schmid, S. Martens, J.C. Stachowiak, N. Liska, D.A. Fletcher, "Forming giant vesicles with controlled membrane composition, asymmetry, and contents", PNAS, vol 108 issue 23, 9431-9436, June 2011. Epub ahead of print, May 2011. [Article]

K. Webster, A. Crow, D.A. Fletcher, "An AFM-based stiffness clamp for dynamic control of rigidity", PLoS ONE, vol. 6 issue 3, e17807, March 2011. [Article]

R. Novak, Y. Zeng, J. Shuga, G. Venugopalan, D.A. Fletcher, M.T. Smith, R.A. Mathies, "Single-Cell multiplex gene detection and sequencing with microfluidically generated agarose emulsions", Angewandte Chemie International Edition, vol. 50 issue 2, 390-395, January 2011. [Article]

W.A. Lam, O.Chaudhuri, A. Crow, K.D. Webster, T. Li, A. Kita, J. Huang, D.A. Fletcher, "Mechanics and contraction dynamics of single platelets and implications for clot stiffening", Nature Materials, vol. 10 No 1, 61-66, January 2011. [Article]


D.A. Fletcher, "On force and function", Molecular Biology of the Cell, vol. 21 issue 22, 3795-6, 15 November 2010. [Abstract]

A. Pasqua, L. Maibaum, G. Oster, D.A. Fletcher, "Large-scale simulations of fluctuating biological membranes", Journal of Chemical Physics, vol. 132 issue 15 article 154107, April 2010. [Abstract]

G. Bao, R.D. Kamm, W. Thomas, W. Hwang, D.A. Fletcher, A.J. Grodzinsky, C. Zhu, M.R. Mofrad, "Molecular Biomechanics: The Molecular Basis of How Forces Regulate Cellular Function", Molecular & Cellular Biomechanics, vol. 3 No. 2, 91-105, March 2010. [Article]

D.A. Fletcher and R.D. Mullins, "Cell mechanics and the cytoskeleton", Nature, vol. 463, 485-492, 28 January, 2010. [Article]


A.P. Liu and D.A. Fletcher, "Biology under construction: in vitro reconstitution of cellular function", Nature Reviews Molecular Cell Biology vol. 10, 644-650, September, 2009. [Article]

D.N. Breslauer, R.N. Maamari, N.A. Switz, W.A. Lam, D.A. Fletcher, "Mobile phone based clinical microscopy for global health applications", PLoS ONE 4(7): e6320, July 2009. [Article]

J.C. Stachowiak, D.L. Richmond, T.H. Li, F. Brochard-Wyart and D.A. Fletcher, "Inkjet formation of unilamellar lipid vesicles for cell-like encapsulation", Lab on a Chip, vol. 9 No. 14, 2003-2009, June 2009. [Article]

D.A. Fletcher and P.L. Geissler, "Active biological materials", Annual Review of Physical Chemistry, vol. 60, 469-486, 2009. [Article]

J.C. Stachowiak, T.H. Li, A. Arora, S. Mitragotri, D.A. Fletcher, "Dynamic control of needle-free jet injection", J. Control Release, vol. 135(2), 104-112, April 2009. [Article]

O. Chaudhuri, S.H. Parekh, W.A. Lam, D.A. Fletcher, "Combined atomic force microscopy and side-view optical imaging for mechanical studies of cells", Nature Methods, vol. 6(5), 383-387, April 2009. [Article]

T.H. Li, J.C. Stachowiak, D.A. Fletcher, "Mixing solutions in inkjet formed vesicles", Methods in Enzymol, vol. 465, 75-94, 2009. [Article]


M.J. Rosenbluth, A. Crow, J.W. Shaevitz, D.A. Fletcher, "Slow Stress Propagation in Adherent Cells" Biophysical J vol. 95, 6052-6059, December 2008.[Article]

S.C. Hsiao, A.K. Crow, W.A. Lam, C.R. Bertozzi, D.A. Fletcher, M.B. Francis, "DNA-coated AFM cantilevers for the investigation of cell adhesion and the patterning of live cells" Angew Chem Int Ed Engl vol. 47, 8473-8477, 2008. [Article]

A.P. Liu, D.L. Richmond, L. Maibaum, S. Pronk, P.L. Geissler, D.A. Fletcher, "Membrane-induced bundling of actin filaments", Nature Physics vol. 4, 789-793, October 2008. [Article]

S. Pronk, P.L. Geissler, D.A. Fletcher, "Limits of filipodium stability" Phys Rev Lett vol. 100, 258102, June 2008. [Article]

M.J. Rosenbluth, W.A. Lam, D.A. Fletcher, "Analyzing cell mechanics in hematologic diseases with microfluidic biophysical flow cytometry" Lab Chip vol. 8, 1062-1070, July 2008. [Article]

J.W. Shaevitz, D.A. Fletcher, "Curvature and torsion in growing actin networks" Phys Biol vol. 5, 26006, June 2008. [Article]

W.A. Lam, M.J. Rosenbluth, D.A. Fletcher, "Increased leukaemia cell stiffness is associated with symptoms of leucostasis in paediatric acute lymphoblastic leukaemia" Br J Haematol vol. 142, 480-501, June 2008. [Article]

J.C. Stachowiak, D.L. Richmond, T.H. Li, A.P. Liu, S.H. Parekh, D.A. Fletcher, "Unilamellar vesicle formation and encapsulation by microfluidic jetting" PNAS, vol. 105, 4697-702, March 2008. [Article]

W.R. Hansen, D.A. Fletcher, "Tonic shock induces detachment of Giardia lamblia" PLoS Negl Trop Dis. 2008 Feb;2(2):e169. [Article]


J.C. Stachowiak, M.G. von Muhlen, T.H. Li, L. Jalilian, S.H. Parekh, D.A. Fletcher, "Piezoelectric control of needle-free transdermal drug delivery" J Control Release vol. 124, 88-97, December 2007. [Abstract]

J.W. Shaevitz, D.A. Fletcher, "Load fluctuations drive actin network growth" PNAS vol. 104, 15688-92, October 2007. [Abstract]

J.W. Shaevitz, D.A. Fletcher, "Enhanced three-dimensional deconvolution microscopy using a measured depth-varying point spread function" JOSA A vol. 24, 2622-7, September 2007. [Abstract]

C.I. Lacayo, Z. Pincus, M.M. van Duijn, C.A. Wilson, D.A. Fletcher, F.B. Gertler, A. Mogilner, J.A. Theriot, "Emergence of large-scale cell morphology and movement from local actin filament growth dynamics" PLoS Biol. vol. 5, e233, September 2007. [Abstract]

J.L. Choy, S.H. Parekh, O. Chaudhuri, A.P. Liu, C. Bustamante, M.J. Footer, J.A. Theriot, D.A. Fletcher, "Differential force microscope for long time-scale biophysical measurements" Review of Scientific Insturments, vol. 78, April 2007. [Abstract]

W.A. Lam, M.J. Rosenbluth, and D.A. Fletcher, "Chemotherapy exposure increases leukemia cell stiffness" Blood, vol. 109, 3505-8, April 2007. [Abstract]

Arora A, Hakim I, Baxter J, Rathnasingham R, Srinivasan R, Fletcher DA, Mitragotri S., "Needle-free delivery of macromolecules across the skin by nanoliter-volume pulsed microjets" PNAS, vol. 104, 4255-60, March 2007. [Abstract]

O.Chaudhuri, S.H. Parekh, and D.A. Fletcher, "Reversible stress softening of actin networks" Nature, vol 445, 295-298, January 2007. [Abstract]


A.P. Liu and D.A.Fletcher, "Actin polymerization serves as a membrane domain switch in model lipid bilayers" Biophysical Journal, vol. 91 4064-4070, December 2006. [Abstract]

C.M. Nelson, M.M. Van Duijn, J.L. Inman, D.A. Fletcher, and M.J. Bissell, "Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures" Science, 13 October 2006. [Abstract]

A.P. Arkin and D.A. Fletcher, "Fast, cheap, and somewhat in control" Genome Biology, 30 August 2006. [Abstract]

W.R. Hansen, O Tulyathan, S.C. Dawson, W.Z. Cande, and D. A. Fletcher, "Giardia lamblia Attachment Force is Insensitive to Surface Treatments" Eukaryotic Cell, April 2006. [Abstract]

M.J. Rosenbluth, W.A. Lam, and D.A. Fletcher, "Force microscopy of nonadherent cells: A comparison of leukemia cell deformability", Biophysical Journal, vol. 90 no. 8, 2994-3003, April 2006. [Abstract]


S.H. Parekh, O. Chaudhuri, J. Theriot, and D.A. Fletcher, "Loading history determines velocity of actin network growth", Nature Cell Biology, vol. 7, no. 12, 1219-1223, 2005. [Abstract]

J.W. Shaevitz, J.Y. Lee, D.A. Fletcher, “Spiroplasma Swim by a Processive Change in Body Helicity”, Cell, vol. 122, no. 6, 941-935, 2005. [Abstract]

A.P. Liu, D.A.Fletcher, “Photopatterning of actin filament structures”, Nano Letters, vol. 5, no. 4, 625-628, 2005. [Abstract]


D. A. Fletcher and J. A. Theriot, “An introduction to cell motility for the physical scientist”, Physical Biology, vol. 1, no. 1, T1-T10, 2004. [Abstract]

S.S. Justice, C. Hung, J.A. Theriot, D.A. Fletcher, G.G. Anderson, M.J. Footer, and S.J. Hultgren, “Differentiation and developmental pathways of uropathogenic E. coli in urinary tract pathogenesis”, PNAS, vol. 101, no. 5, pp. 1333-1338, 2004. [Abstract]


D.A. Fletcher, G.S. Kino, and K.E. Goodson, “Thermal microscopy with a microfabricated solid immersion lens”, Microscale Thermophysical Engineering, vol. 7, no. 4, pp. 267-273, 2003. (cover image)

P.A. Giardini, D.A. Fletcher, J.A. Theriot, “Compression forces generated by actin comet tails on lipid vesicles”, PNAS, vol. 100, no. 11, pp. 6493-6498, 2003. (Science Editor’s Choice, June 6, 2003) [Abstract]


D.A. Fletcher, D.V. Palanker, P. Huie, J. Miller, M.F. Marmor, and M.S. Blumenkranz, “Intravascular drug delivery with the pulsed liquid microjet,” Archives of Ophthalmology, vol. 120, pp. 1206-1208, 2002. [Abstract]

K.B. Crozier, D.A. Fletcher, G.S. Kino, and C.F. Quate, “Micromachined silicon nitride solid immersion lens”, JMEMS, vol. 11, pp. 470-478, 2002.


D.A. Fletcher, K.B. Crozier, K.W. Guarini, S.C. Minne, G.S. Kino, C.F. Quate, and K. E. Goodson, “Microfabricated silicon solid immersion lens,” JMEMS, vol. 10, pp. 450-459, 2001.

D.A. Fletcher, K.B. Crozier, C.F. Quate, G.S. Kino, K.E. Goodson, D. Simanovskii, and D.V. Palanker, “Refraction contrast imaging with a scanning microlens”, Applied Physics Letters, vol. 78, pp. 3589-3591, 2001.

D.A. Fletcher, K.E. Goodson, and G.S. Kino, “Focusing in microlenses close to a wavelength in diameter,” Optics Letters, vol. 26, pp. 399-401, 2001. [Abstract]

D. A. Fletcher and D.V. Palanker, “Pulsed liquid microjet for microsurgery,” Applied Physics Letters, vol. 78, pp. 1933-1935, 2001. Nature News, April 3, 2001. New Scientist News, April 25, 2001.


D.A. Fletcher, K.B. Crozier, G.S. Kino, C.F. Quate, K.E. Goodson, D. Simanovskii, and D.V. Palanker, “Near-field infrared imaging with a microfabricated solid immersion lens,” Applied Physics Letters, vol. 77, pp. 2109-2111, 2000.


T. Sulchek, S.C. Minne, J.D. Adams, D.A. Fletcher, A. Atalar, C.F. Quate, and D.M. Adderton, “Dual integrated actuators for extended range high speed atomic force microscopy,” Applied Physics Letters, vol. 75, pp. 1637-1639, 1999.