Fletcher Lab
Cellular and Molecular Mechanics 
  PUBLICATIONS
Journal articles

2009

     D.A. Fletcher and P.L. Geissler, "Active biological materials", Annual Review of Physical Chemistry, vol. 60, 469-486, 2009. [Article]
     J.C. Stachowiak, T.H. Li, A. Arora, S. Mitragotri, D.A. Fletcher, "Dynamic control of needle-free jet injection", J. Control Release, vol. 135(2), 104-112, April 2009. [Article]
     O. Chaudhuri, S.H. Parekh, W.A. Lam, D.A. Fletcher, "Combined atomic force microscopy and side-view optical imaging for mechanical studies of cells", Nature Methods, vol. 6(5), 383-387, May 2009. [Article]

2008

     M.J. Rosenbluth, A. Crow, J.W. Shaevitz, D.A. Fletcher, "Slow Stress Propagation in Adherent Cells" Biophysical J vol. 95, 6052-6059, December 2008.[Article]
     S.C. Hsiao, A.K. Crow, W.A. Lam, C.R. Bertozzi, D.A. Fletcher, M.B. Francis, "DNA-coated AFM cantilevers for the investigation of cell adhesion and the patterning of live cells" Angew Chem Int Ed Engl vol. 47, 8473-8477, 2008. [Article]
     A.P. Liu, D.L. Richmond, L. Maibaum, S. Pronk, P.L. Geissler, D.A. Fletcher, "Membrane-induced bundling of actin filaments", Nature Physics vol. 4, 789-793, October 2008.
[Article]
     S. Pronk, P.L. Geissler, D.A. Fletcher, "Limits of filipodium stability" Phys Rev Lett vol. 100, 258102, June 2008.[Article]
     M.J. Rosenbluth, W.A. Lam, D.A. Fletcher, "Analyzing cell mechanics in hematologic diseases with microfluidic biophysical flow cytometry" Lab Chip vol. 8, 1062-1070, July 2008. [Article]
     J.W. Shaevitz, D.A. Fletcher, "Curvature and torsion in growing actin networks" Phys Biol vol. 5, 26006, June 2008.[Article]
     W.A. Lam, M.J. Rosenbluth, D.A. Fletcher, "Increased leukaemia cell stiffness is associated with symptoms of leucostasis in paediatric acute lymphoblastic leukaemia" Br J Haematol vol. 142, 480-501, June 2008.[Article]
     J.C. Stachowiak, D.L. Richmond, T.H. Li, A.P. Liu, S.H. Parekh, D.A. Fletcher, "Unilamellar vesicle formation and encapsulation by microfluidic jetting" PNAS, vol. 105, 4697-702, March 2008. [Article]
     W.R. Hansen, D.A. Fletcher, "Tonic shock induces detachment of Giardia lamblia" PLoS Negl Trop Dis. 2008 Feb;2(2):e169.[Article]

2007

     J.C. Stachowiak, M.G. von Muhlen, T.H. Li, L. Jalilian, S.H. Parekh, D.A. Fletcher, "Piezoelectric control of needle-free transdermal drug delivery" J Control Release vol. 124, 88-97, December 2007.

     J.W. Shaevitz, D.A. Fletcher, "Load fluctuations drive actin network growth" PNAS vol. 104, 15688-92, October 2007.
     J.W. Shaevitz, D.A. Fletcher, "Enhanced three-dimensional deconvolution microscopy using a measured depth-varying point spread function" JOSA A vol. 24, 2622-7, September 2007.
     C.I. Lacayo, Z. Pincus, M.M. van Duijn, C.A. Wilson, D.A. Fletcher, F.B. Gertler, A. Mogilner, J.A. Theriot, "Emergence of large-scale cell morphology and movement from local actin filament growth dynamics" PLoS Biol. vol. 5, e233, September 2007.
     J.L. Choy, S.H. Parekh, O. Chaudhuri, A.P. Liu, C. Bustamante, M.J. Footer, J.A. Theriot, D.A. Fletcher, "Differential force microscope for long time-scale biophysical measurements" Review of Scientific Insturments, vol. 78, April 2007. [PDF]
     W.A. Lam, M.J. Rosenbluth, and D.A. Fletcher, "Chemotherapy exposure increases leukemia cell stiffness" Blood, vol. 109, 3505-8, April 2007. [PDF] [Supplemental Materials]
      Arora A, Hakim I, Baxter J, Rathnasingham R, Srinivasan R, Fletcher DA, Mitragotri S., "Needle-free delivery of macromolecules across the skin by nanoliter-volume pulsed microjets" PNAS, vol. 104, 4255-60, March 2007. [PDF]
     O.Chaudhuri, S.H. Parekh, and D.A. Fletcher, "Reversible stress softening of actin networks" Nature, vol 445, 295-298, January 2007. [PDF]

2006

     A.P. Liu and D.A.Fletcher, "Actin polymerization serves as a membrane domain switch in model lipid bilayers" Biophysical Journal, vol. 91 4064-4070, December 2006. [PDF] [New and Notable Commentary]
     C.M. Nelson, M.M. Van Duijn, J.L. Inman, D.A. Fletcher, and M.J. Bissell, "Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures" Science, 13 October 2006. [PDF]
     A.P. Arkin and D.A. Fletcher, "Fast, cheap, and somewhat in control" Genome Biology, 30 August 2006. [PDF]
     W.R. Hansen, O Tulyathan, S.C. Dawson, W.Z. Cande, and D. A. Fletcher, "Giardia lamblia Attachment Force is Insensitive to Surface Treatments" Eukaryotic Cell, April 2006. [PDF]
     M.J. Rosenbluth, W.A. Lam, and D.A. Fletcher, "Force Microscopy of Non-Adherent Cells: A Comparison of Leukemia Cell Deformability", Biophysical Journal, vol. 90 no. 8, 2994-3003, April 2006. [PDF]

2005

     S. H. Parekh, O. Chaudhuri, J. Theriot, and D.A. Fletcher, "Loading HIstory Determines Velocity of Actin Network Growth", Nature Cell Biology, vol. 7, no. 12, 1219-1223, 2005. [PDF]
     J.W. Shaevitz, J.Y. Lee, D.A. Fletcher, “Spiroplasma Swim by a Processive Change in Body Helicity”, Cell, vol. 122, no. 6, 941-935, 2005. [PDF] [Previewed in Cell]
     A.P. Liu, D.A.Fletcher, “Photopatterning of actin filament structures”, Nano Letters, vol. 5, no. 4, 625-628, 2005. [PDF]

2004

     D. A. Fletcher and J. A. Theriot, “An introduction to cell motility for the physical scientist”, Physical Biology, vol. 1, no. 1, T1-T10, 2004.
     S. S. Justice, C. Hung, J. A. Theriot, D. A. Fletcher, G. G. Anderson, M. J. Footer, and S. J. Hultgren, “Differentiation and developmental pathways of uropathogenic E. coli in urinary tract pathogenesis”, PNAS, vol. 101, no. 5, pp. 1333-1338, 2004.

2003

     D. A. Fletcher, G. S. Kino, and K. E. Goodson, “Thermal microscopy with a microfabricated solid immersion lens”, Microscale Thermophysical Engineering, vol. 7, no. 4, pp. 267-273, 2003. (cover image)
     P. A. Giardini, D. A. Fletcher, J. A. Theriot, “Compression forces generated by actin comet tails on lipid vesicles”, PNAS, vol. 100, no. 11, pp. 6493-6498, 2003. (Science Editor’s Choice, June 6, 2003)

2002

     D. A. Fletcher, D. V. Palanker, P. Huie, J. Miller, M. F. Marmor, and M. S. Blumenkranz, “Intravascular drug delivery with the pulsed liquid microjet,” Archives of Ophthalmology, vol. 120, pp. 1206-1208, 2002.
     K. B. Crozier, D. A. Fletcher, G. S. Kino, and C. F. Quate, “Micromachined silicon nitride solid immersion lens,” JMEMS, vol. 11, pp. 470-478, 2002.

2001

     D. A. Fletcher, K. B. Crozier, K. W. Guarini, S. C. Minne, G. S. Kino, C. F. Quate, and K. E. Goodson, “Microfabricated silicon solid immersion lens,” JMEMS, vol. 10, pp. 450-459, 2001.
     D. A. Fletcher, K. B. Crozier, C. F. Quate, G. S. Kino, K. E. Goodson, D. Simanovskii, and D. V. Palanker, “Refraction contrast imaging with a scanning microlens,” Applied Physics Letters, vol. 78, pp. 3589-3591, 2001.
     D. A. Fletcher, K. E. Goodson, and G. S. Kino, “Focusing in microlenses close to a wavelength in diameter,” Optics Letters, vol. 26, pp. 399-401, 2001.
     D. A. Fletcher and D. V. Palanker, “Pulsed liquid microjet for microsurgery,” Applied Physics Letters, vol. 78, pp. 1933-1935, 2001. (Nature News, April 3, 2001; New Scientist News, April 25, 2001)

2000

     D. A. Fletcher, K. B. Crozier, G. S. Kino, C. F. Quate, K. E. Goodson, D. Simanovskii, and D. V. Palanker, “Near-field infrared imaging with a microfabricated solid immersion lens,” Applied Physics Letters, vol. 77, pp. 2109-2111, 2000.

1999

     T. Sulchek, S. C. Minne, J. D. Adams, D. A. Fletcher, A. Atalar, C. F. Quate, and D. M. Adderton, “Dual integrated actuators for extended range high speed atomic force microscopy,” Applied Physics Letters, vol. 75, pp. 1637-1639, 1999.