Programming multicellular assembly with synthetic cell adhesion molecules
Nature (2022); DOI: 10.1038/s41586-022-05622-z
Stevens AJ, Harris AR, Gerdts J, Kim KH, Trentesaux C, Ramirez JT, McKeithan WL, Fattahi F, Klein OD, Fletcher DA, Lim WA
Publications
In Vitro Reconstitution
The molecular mechanism of load adaptation by branched actin networks
eLife (2022); DOI: 10.7554/eLife.73145
Li TD*, Bieling P*, Weichsel J, Mullins RD, Fletcher DA
Forming and loading giant unilamellar vesicles with acoustic jetting
Biomicrofluidics (2020); DOI: 10.1063/5.0021742
Armstrong M, Vahey MD, Hunt TP, Fletcher DA
Quantitative biophysical analysis defines key components modulating recruitment of the GTPase KRAS to the plasma membrane
Journal of Biological Chemistry (2018); DOI: 10.1074/jbc.RA118.005669
Lakshman B, Messing S, Schmid EM, Clogston JD, Gillette WK, Esposito D, Kessing B, Fletcher DA, Nissley DV, McCormick F, Stephen AG, Jean-Francois FL
Low-Fidelity Assembly of Influenza A Virus Promotes Escape from Host Cells
Cell (2018); DOI: 10.1016/j.cell.2018.10.056
Vahey MD, Fletcher DA
One and one is not two: taking a fresh look at membrane interfaces
Nature Reviews Molecular Cell Biology (2018); DOI: 10.1038/s41580-018-0057-3
Belardi B, Fletcher DA
Claudin-4 reconstituted in unilamellar vesicles is sufficient to form tight interfaces that partition membrane proteins
Journal of Cell Science (2018); DOI: 10.1242/jcs.221556
Belardi B, Son S, Vahey MD, Wang J, Hou J, Fletcher DA
Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets
Cell (2018); DOI: 10.1016/j.cell.2018.05.059
Bakalar MH, Joffe AM, Schmid EM, Son S, Podolski M, Fletcher DA
Size-dependent protein segregation at membrane interfaces
Nature Physics (2016); DOI: 10.1038/nphys3678
Schmid EM*, Bakalar MH*, Choudhuri K*, Weichsel J, Ann HS, Geissler PL, Dustin ML, Fletcher DA
Force Feedback Controls Motor Activity and Mechanical Properties of Self-Assembling Branched Actin Networks
Cell (2016); DOI: 10.1016/j.cell.2015.11.057
Bieling P*, Li TD*, Weichsel J, McGorty R, Jreij P, Huang B, Fletcher DA, Mullins RD
Reconstitution of proteins on electroformed unilamellar vesicles
Methods in Cell Biology (2015); DOI: 10.1016/bs.mcb.2015.02.004
Schmid EM, Richmond DL, Fletcher DA
Micropattern-guided assembly of overlapping pairs of dynamic microtubules
Meth. Enzymol. 540, 339–360 (2014)
F.J. Fourniol, T.D. Li, P. Bieling, R.D. Mullins, D.A. Fletcher, T. Surrey
Cytoplasmic volume modulates spindle size during embryogenesis
Science (2013); DOI: 10.1126/science.1243147
Good MC, Vahey MD, Skandarajah A, Fletcher DA, Heald R
Membrane bending by protein-protein crowding
Nature Cell Biology (2012); DOI: 10.1038/ncb2561
Stachowiak JC, Schmid EM, Ryan CJ, Ann HS, Sasaki DY, Sherman MB, Geissler PL, Fletcher DA, Hayden CC
Actin filament curvature biases branching direction
PNAS (2012); DOI: 10.1073/pnas.1114292109
V.I. Risca, E.B. Wang, O. Chaudhuri, J.J. Chia, P.L. Geissler, D.A. Fletcher
Forming giant vesicles with controlled membrane composition, asymmetry, and contents
PNAS (2011); DOI: 10.1073/pnas.1016410108
D.L. Richmond, E.M. Schmid, S. Martens, J.C. Stachowiak, N. Liska, D.A. Fletcher
Large-scale simulations of fluctuating biological membranes
J Chem Phys. 132, 154107 (2010)
A. Pasqua, L. Maibaum, G. Oster, D.A. Fletcher
Biology under construction: in vitro reconstitution of cellular function
Nature Reviews Molecular Cell Biology (2009); DOI: 10.1038/nrm2746
Liu AP, Fletcher DA
Membrane-induced bundling of actin filaments
Nature Physics (2008); DOI: 10.1038/nphys1071
Liu AP, Richmond DL, Maibaum L, Pronk S, Geissler PL, Fletcher DA
Curvature and torsion in growing actin networks
Phys Biol. 5, 026006 (2008)
J.W. Shaevitz, D.A. Fletcher
Load fluctuations drive actin network growth
PNAS (2007); DOI: 10.1073/pnas.0702601104
Shaevitz JW, Fletcher DA
Reversible stress softening of actin networks
Nature (2007); DOI: 10.1038/nature05459
Chaudhuri O, Parekh SH, Fletcher DA
Actin polymerization serves as a membrane domain switch in model lipid bilayers
Biophysical Journal (2006); DOI: 10.1529/biophysj.106.090852
Liu AP, Fletcher DA
Loading history determines velocity of actin network growth
Nature Cell Biology (2005); DOI: 10.1038/ncb1336
Parekh SH, Chaudhuri O, Theriot J, Fletcher DA
Photopatterning of actin filament structures
Nano Lett. 5, 625–628 (2005)
A.P. Liu, D.A.Fletcher
Compression forces generated by actin comet tails on lipid vesicles
PNAS (2003); DOI: 10.1073/pnas.1031670100
Giardini PA, Fletcher DA, Theriot JA